Using Biological Properties of Viruses to Develop Experimental Models for Testing Antiviral Compounds
Il’ya Vinogradov, Galina Kochneva, Elena Ryabchikova
State Research Center of Virology and Biotechnology “Vector”, Koltsovo, Novosibirsk region, RUSSIA 630559
The development of effective chemical antiviral compounds is one of the most important directions of modern science. There are very few examples of chemical antiviral preparations used in medical practice. One of these preparations is remantadine, which affects the operation of endosomes: endosomes are responsible for uncoating of influenza virus and release of its genome into cytoplasm [5,7]. The invention of new antiviral compounds is laborious and expensive work, including sequential testing of antiviral activity in cell cultures and in animal models.
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BTWC Meeting of States Parties
Geneva : 6 – 10 December 2004
by Graham S. Pearson
As reported in ASA Newsletter 04-4 (August 27, 2004), the Meeting of Experts of the States Parties of the Biological and Toxin Weapons Convention (BTWC) held in Geneva on 19 to 30 July 2004 made significant progress in considering the two topics identified for 2004:
iii. Enhancing international capabilities for responding to, investigating and mitigating the effects of cases of alleged use of biological and toxin weapons or suspicious outbreaks of disease;
iv. Strengthening and broadening national and international institutional efforts and existing mechanisms for the surveillance, detection, diagnosis and combating of infectious diseases affecting humans, animals and plants;
The Meeting of Experts produced a report which contained as Annex II a paper prepared by the Chairman listing the considerations, lessons, perspectives, recommendations, conclusions, and proposals drawn from the presentations, statements, working papers and interventions made by delegations on the topics under discussion at the Meeting.
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Editor’s Note: There is a comparative lack of Russian-language based material describing Soviet and, later, Russian activities in the biological field. This article is largely based on such material and should therefore be of special interest to the ASA family of professionals around the world. Our thanks to John Hart, ASA Correspondent and a Researcher with the CBW Project at SIPRI.
A Historical Note:
The 50th Anniversary of the founding of Russia’s Virology Center at Sergiev Posad
by John Hart (SIPRI)*
The Virology Center of the Scientific-Research Institute of Microbiology of the Ministry of Defense of the Russian Federation, located at Sergiev Posad (formerly Zagorsk), is an important component of Russia’s biological defense establishment. It was created in 1953 when the Scientific Research Institute of Sanitation of the Ministry of Health of the USSR was transferred to the Ministry of Defense and renamed the Scientific Research Institute of Sanitation of the Ministry of Defense of the USSR.
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an inside look at ASA 05-1
| The Professional Library |
2 |
| CBMTS - Industry IV |
3 |
| 36th World Congress on Military Medicine |
8 |
| International Symposium NBC Terrorism |
10 |
International Cooperation Events |
14 |
| ON THE STREET |
15 |
| Results-based Budgeting at the OPCW |
23 |
| 4th SISPAT/CBMTS: Pre-Symposium WorkShop |
24 |
| In Memoriam |
28 |
| GAO Reports |
29 |
| Recent Contracts |
29 |
| BioScope‘05 |
32 |
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